• Corpus ID: 34538322

Chronic Oral Consumption of Ethanolic Extract of Picralima Nitida ( Akuamma ) Seed Induced Histopathological changes On the Testes of Adult Wistar Rats

@inproceedings{SolomonChronicOC,
  title={Chronic Oral Consumption of Ethanolic Extract of Picralima Nitida ( Akuamma ) Seed Induced Histopathological changes On the Testes of Adult Wistar Rats},
  author={Ijioma Solomon and Gabriel Joseph Ekandem}
}
Histomorphological effect of chronic consumption of ethanolic extract of Picralima nitida seed on the Testes of adult albino wistar male rats was investigated usin g 20 male albino wistar rats; they were distributed into 5 rats in each group. Group 1 was the control group while gro ups 2 to group 4 were the experimental groups. Grou p 1 was given distilled water and normal rat feed, Group 2 was given 250mg/kg serving as low dose, group 3 was given 350mg/kg as middle dose and group 4 was given… 

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References

SHOWING 1-10 OF 10 REFERENCES
Anti-inflammatory, antipyretic and anti-malarial activities of a West African medicinal plant--Picralima nitida.
TLDR
The results confirm the medicinal value of this plant and thus justify its use by natives of W. Africa.
Evaluation of the antimicrobial property of the stem bark of Picralima nitida (Apocynaceae)
The basic fraction (BF) of the methanol extract of the stem bark of Picralima nitida (family Apocynaceae) exhibited significant antimicrobial activity against a wide range of Gram‐positive bacteria
Medicinal Plants in Tropical West Africa
TLDR
The central nervous system, particularly the adrenal cortex, is involved in the regulation of sexual activity and the action of sex hormones and thyroid hormones is studied.
Clinical oriented anatomy Hagerstown, MD: Lipincott
  • 2010
Jaypee Brothers medical publishers LTD
  • Pg. 279 – 287. 12. Tapsell L., Hemphill I., Cobiac L.
  • 2006
Contribution to ethnobotanical & Floristic studies in Cameroun
  • Traditional Medicine & Pharmacopoeia
  • 1996
Akuammine: an antimalarial indolemonoterpene alkaloid of Picralima nitida seeds.
The useful plants of West Tropical Africa.
“ Chronic Oral Consumption of Ethanolic Extract of Picralima Nitida ( Akuamma ) Seed Iinduced Histopathological changes On the Testes of Adult Wistar Rats ” Int . J . of Pharm . Res . & All