Chronic Opioid Therapy and Central Sensitization in Sickle Cell Disease.

@article{Carroll2016ChronicOT,
  title={Chronic Opioid Therapy and Central Sensitization in Sickle Cell Disease.},
  author={C Patrick Carroll and Sophie M. Lanzkron and Carlton Haywood and Kasey B. Kiley and Megan Pejsa and Gyasi Moscou-Jackson and Jennifer A. Haythornthwaite and Claudia M. Campbell},
  journal={American journal of preventive medicine},
  year={2016},
  volume={51 1 Suppl 1},
  pages={
          S69-77
        }
}
Chronic opioid therapy (COT) for chronic non-cancer pain is frequently debated, and its effectiveness is unproven in sickle cell disease (SCD). The authors conducted a descriptive study among 83 adult SCD patients and compared the severity of disease and pain symptoms among those who were prescribed COT (n=29) with those who were not using COT. All patients completed baseline laboratory pain assessment and questionnaires between January 2010 and June 2014. Thereafter, participants recorded… CONTINUE READING
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