Chronic Maternal Vitamin B12 Restriction Induced Changes in Body Composition & Glucose Metabolism in the Wistar Rat Offspring Are Partly Correctable by Rehabilitation

@article{Kumar2014ChronicMV,
  title={Chronic Maternal Vitamin B12 Restriction Induced Changes in Body Composition \& Glucose Metabolism in the Wistar Rat Offspring Are Partly Correctable by Rehabilitation},
  author={Kalle Anand Kumar and Anumula Lalitha and Umakar S Reddy and Giriraj Ratan Chandak and Shantanu P Sengupta and Manchala Raghunath},
  journal={PLoS ONE},
  year={2014},
  volume={9}
}
Maternal under-nutrition increases the risk of developing metabolic diseases. We studied the effects of chronic maternal dietary vitamin B12 restriction on lean body mass (LBM), fat free mass (FFM), muscle function, glucose tolerance and metabolism in Wistar rat offspring. Prevention/reversibility of changes by rehabilitating restricted mothers from conception or parturition and their offspring from weaning was assessed. Female weaning Wistar rats (n = 30) were fed ad libitum for 12 weeks, a… 

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