Chronic Lyme disease: in defense of the scientific enterprise

@article{Baker2010ChronicLD,
  title={Chronic Lyme disease: in defense of the scientific enterprise},
  author={Phillip J. Baker},
  journal={The FASEB Journal},
  year={2010},
  volume={24},
  pages={4175 - 4177}
}
  • P. Baker
  • Published 1 November 2010
  • Medicine
  • The FASEB Journal
There is no better example of a relentless attack on evidence‐based biomedical research and the integrity of outstanding scientists than that associated with the treatment of a poorly defined condition called “chronic Lyme disease.” Here, a scientifically naive general population, the lay press, and legislators, who in most instances are unable to evaluate and judge scientific evidence properly, have been misled by patient advocate groups to believe that extended antibiotic therapy is the best… 
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17 Citations
Background Citations
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17 Citations

The Lyme disease chronicles, continued: Chronic Lyme disease: in defense of the patient enterprise
TLDR
In his attack on “Lyme disease activists” who have besmirched the “scientific enterprise,” Phillip Baker misrepresents the controversy over tick-borne diseases and cites a long list of medical societies that “are in agreement” with the IDSA Lyme recommendations.
Bullying Borrelia: when the culture of science is under attack.
  • P. AuwaerterM. Melia
  • Biology
    Transactions of the American Clinical and Climatological Association
  • 2012
TLDR
Although Lyme disease responds to short courses of antibiotics, tick-borne Borrelia burgdorferi has been advanced by some as a frequent explanation for medically unexplained symptoms, and practitioners liberally prescribe nostrums in a belief that this eradicates suspected infection.
Lyme disease: The great controversy
TLDR
This strange story begins with the disease's original characterization in the USA in the early 1970s, when a surprising number of children in Lyme and Old Lyme, Connecticut, were diagnosed as having juvenile rheumatoid arthritis.
Hyperbaric Oxygen Therapy and Chronic Lyme Disease: The Controversy and the Evidence
TLDR
An HBOT registry for Lyme disease and CLD would be an important tool to better understand the number of patients treated and whether or not HBOT has a beneficial effect on this puzzling and controversial condition.
Lyme Borreliosis: Is there a preexisting (natural) variation in antimicrobial susceptibility among Borrelia burgdorferi strains?
  • E. Hodžić
  • Biology, Medicine
    Bosnian journal of basic medical sciences
  • 2015
TLDR
A number of host cytokines were up- or down-regulated in tissues of both shame- and antibiotic-treated mice in the absence of histopathology, indicating a lack of host response to the presence of antimicrobial tolerant/resistant spirochetes.
Lyme disease.
Persistence of Non-Cultivable Borrelia burgdorferi Following Antibiotic Treatment : Critical Need for Further Research
TLDR
Prevalence of human disease continues to rise, as does the geographic distribution of endemic areas, and interest in Lyme disease is rising globally, as infected ticks and reservoir hosts are extending their range from the United States, as well as an increase in prevalence throughout Europe and Asia.
Lyme borreliosis in Europe.
Despite improvements in prevention, diagnosis and treatment, Lyme borreliosis (LB) is still the most common arthropod-borne disease in temperate regions of the northern hemisphere, with risk of…
Is It Possible to Make a Correct Diagnosis of Lyme Disease on Symptoms Alone? Review of Key Issues and Public Health Implications.
  • P. Baker
  • Medicine
    The American journal of medicine
  • 2019
LYME DISEASE AND RELAPSING FEVER SPIROCHETES
TLDR
This chapter reviews currently available technologies for live imaging that have been used on B. burgdorferi and that have revealed significant new findings and discusses the methodologies to be described here, which are highly varied, as are the processes studied and the resulting knowledge gained.
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References

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