Chronic L-NAME hypertension in rats and autoregulation of juxtamedullary preglomerular vessels.

@article{Bouriquet1995ChronicLH,
  title={Chronic L-NAME hypertension in rats and autoregulation of juxtamedullary preglomerular vessels.},
  author={N. Bouriquet and D. Casellas},
  journal={The American journal of physiology},
  year={1995},
  volume={269 2 Pt 2},
  pages={
          F190-7
        }
}
The impact of chronic NG-nitro-L-arginine methyl ester (L-NAME)-induced hypertension (20 mg.kg-1.day-1 po, for 25 days) on pressure responsiveness was assessed in vessels ranging from arcuate arteries (ArcA) to juxtaglomerular afferent arterioles (JAA), using videomicroscopy and blood-perfused juxtamedullary nephron (JMN) preparations. Respective tail-cuff pressures of control and L-NAME rats were 127 +/- 2 (n = 8) and 173 +/- 4 mmHg (n = 5). Corresponding vessels of both groups had similar… Expand
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