Chronic Intermittent Ethanol Treatment Selectively Alters N-Methyl-d-aspartate Receptor Subunit Surface Expression in Cultured Cortical Neurons

@article{Qiang2007ChronicIE,
  title={Chronic Intermittent Ethanol Treatment Selectively Alters N-Methyl-d-aspartate Receptor Subunit Surface Expression in Cultured Cortical Neurons},
  author={Mei Qiang and A. Denny and M. Ticku},
  journal={Molecular Pharmacology},
  year={2007},
  volume={72},
  pages={102 - 95}
}
  • Mei Qiang, A. Denny, M. Ticku
  • Published 2007
  • Chemistry, Medicine
  • Molecular Pharmacology
  • A chronic intermittent ethanol (CIE) exposure regimen consists of repeated episodes of ethanol intoxication and withdrawal. CIE treatment has been reported to result in a significant enhancement of N-methyl-d-aspartate (NMDA) receptor-mediated synaptic responses in vivo, and trafficking of NMDA receptors is emerging a key regulatory mechanism that underlies the channel function. Therefore, in the present study, we examined the effects of CIE on NMDA receptor subunit surface expression. Cultured… CONTINUE READING
    Regulation of NMDA receptor subunits after acute ethanol treatment in rat brain.
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