Chronic Inhalation Toxicity of a Kaolin-Based Refractory Ceramic Fiber in Syrian Golden Hamsters

@inproceedings{Mcconnell1995ChronicIT,
  title={Chronic Inhalation Toxicity of a Kaolin-Based Refractory Ceramic Fiber in Syrian Golden Hamsters},
  author={Ernest E. Mcconnell and Richard W. Mast and Thomas W. Hesterberg and J{\"o}rg Chevalier and Paul Kotin and Diane Morris Bernstein and Philippe Th{\'e}venaz and Leon R Glass and Richard N. Anderson},
  year={1995}
}
AbstractKaolin-based refractory ceramic fiber (RCF) is a man-made vitreous fiber used primarily in industrial high-temperature applications, especially for insulation of furnaces and kilns. Because of its increasing use and potential for human exposure, a chronic toxicity/ carcinogenicity inhalation study was conducted in Syrian golden hamsters. Two groups of 140 weanling male hamsters were exposed via nose-only inhalation to either HEPA-filtered air (chamber controls) or 30 mg/m3 (-220 fibers… CONTINUE READING

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