Chronic Inflammatory Disease in the Pancreas, Kidney and Salivary Glands of English Cocker Spaniels and Dogs of Other Breeds Shows Similar Histological Features to Human IgG4-related Disease.

@article{Coddou2020ChronicID,
  title={Chronic Inflammatory Disease in the Pancreas, Kidney and Salivary Glands of English Cocker Spaniels and Dogs of Other Breeds Shows Similar Histological Features to Human IgG4-related Disease.},
  author={Marcelo Coddou and Fernando Constantino-Casas and Timothy J. Scase and Michael Joseph Day and Barbara A. Blacklaws and Penny Watson},
  journal={Journal of comparative pathology},
  year={2020},
  volume={177},
  pages={
          18-33
        }
}
  • Marcelo Coddou, Fernando Constantino-Casas, +3 authors Penny Watson
  • Published 2020
  • Medicine, Biology
  • Journal of comparative pathology
  • Chronic pancreatitis (CP) is a common disease in the English cocker spaniel (ECS) and is characterized histologically by duct destruction, interlobular fibrosis and dense periductular and perivenous lymphocytic aggregates. These features are also found in human autoimmune pancreatitis type 1, part of a glucocorticoid-responsive, multiorgan syndrome, newly recognized as IgG4-related disease (IgG4-RD). Human IgG4-RD affects one or several organs, often showing a predominance of IgG4+ plasma cells… CONTINUE READING

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