Chronic Hepatitis C Virus Infection and the Proinflammatory Effects of Injection Drug Use.

Abstract

BACKGROUND  Chronic inflammation, as defined by persistent immune activation, is associated with adverse clinical outcomes. People who inject drugs (PWID) have evidence of persistent immune activation. Here, in a cohort of PWID with or without hepatitis C virus (HCV) infection, we sought to dissect out the contribution of chronic HCV infection (common in… (More)

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