Chronic Back Pain Is Associated with Alterations in Dopamine Neurotransmission in the Ventral Striatum.

@article{Martikainen2015ChronicBP,
  title={Chronic Back Pain Is Associated with Alterations in Dopamine Neurotransmission in the Ventral Striatum.},
  author={Ilkka Kristian Martikainen and Emily B Nuechterlein and Marta Peci{\~n}a and Tiffany M. Love and Chelsea M. Cummiford and Carmen Rene{\'e} Green and Christian S. Stohler and J K Zubieta},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2015},
  volume={35 27},
  pages={9957-65}
}
UNLABELLED Back pain is common in the general population, but only a subgroup of back pain patients develops a disabling chronic pain state. The reasons for this are incompletely understood, but recent evidence implies that both preexisting and pain-related variations in the structure and function of the nervous system may contribute significantly to the development of chronic pain. Here, we addressed the role of striatal dopamine (DA) D2/D3 receptor (D2/D3R) function in chronic non-neuropathic… CONTINUE READING
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