Chromosomes 12 and 16 workshop.

  title={Chromosomes 12 and 16 workshop.},
  author={S. D. Detera-Wadleigh},
  journal={American journal of medical genetics},
  volume={88 3},
Recent linkage results independently derived from a large French Canadian pedigree and Danish kindreds coupled with supportive data from other studies provide compelling evidence for a bipolar disorder susceptibility locus on chromosome 12q23-q24. The idea is further strengthened by the finding that Darier's disease, which maps to this region, has been shown to cosegregate with affective disorder in a family. This linkage finding, however, was not supported in other independent genome scans. On… CONTINUE READING
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