Chromosome territory repositioning induced by PHA-activation of lymphocytes: A 2D and 3D appraisal

@inproceedings{Ioannou2015ChromosomeTR,
  title={Chromosome territory repositioning induced by PHA-activation of lymphocytes: A 2D and 3D appraisal},
  author={Dimitrios Ioannou and Lakshmi Kandukuri and Joe Leigh Simpson and H. G. Tempest},
  booktitle={Molecular Cytogenetics},
  year={2015}
}
BackgroundGenomes and by extension chromosome territories (CTs) in a variety of organisms exhibit nonrandom organization within interphase nuclei. CTs are susceptible to movement upon induction by a variety of stimuli, including: cell differentiation, growth factors, genotoxic agents, proliferating status, and stimulants that induce novel transcription profiles. These findings suggest nuclear architecture can undergo reorganization, providing support for a functional significance of CT… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 41 REFERENCES

Functional implications of genome topology

  • Nature Structural &Molecular Biology
  • 2013
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