Chromosome studies in human in vitro fertilization

  title={Chromosome studies in human in vitro fertilization},
  author={Roslyn R. Angell and Adly Templeton and Robert John Aitken},
  journal={Human Genetics},
The chromosome constitution of 22 human preimplantation embryos from donor oocytes fertilized in vitro by donor sperm was studied to assess the contribution of lethal chromosome anomalies to the high failure rate of implantation of in vitro fertilized embryos after embryo transfer in infertile women. Evidence was found of nondisjunction, resulting in trisomy, monosomy, and nullosomy; structural abnormalities; haploidy; and triploidy. Despite the lethality of their chromosome complements, these… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 40 references

Newton M (eds) Scientific foundations of obstetrics and gynaecology

  • RG Edwards
  • 1977
Highly Influential
4 Excerpts

Effect of ovarian hyperstimulation on chromosome aberration and sister chromatid exchange on in vivo fertilized oocytes

  • F Sato, RP Marrs
  • Fertil Steril
  • 1984

La parthenogdn6se in vitro dans l'esp6ce humaine

  • M Plachot, J Mandelbaum, J de Grouchy
  • Ann Genet (Paris)
  • 1984
1 Excerpt

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