Chromosome studies in human in vitro fertilization

@article{Angell1986ChromosomeSI,
  title={Chromosome studies in human in vitro fertilization},
  author={Roslyn R. Angell and Adly Templeton and Robert John Aitken},
  journal={Human Genetics},
  year={1986},
  volume={72},
  pages={333-339}
}
The chromosome constitution of 22 human preimplantation embryos from donor oocytes fertilized in vitro by donor sperm was studied to assess the contribution of lethal chromosome anomalies to the high failure rate of implantation of in vitro fertilized embryos after embryo transfer in infertile women. Evidence was found of nondisjunction, resulting in trisomy, monosomy, and nullosomy; structural abnormalities; haploidy; and triploidy. Despite the lethality of their chromosome complements, these… CONTINUE READING

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