Chromosome regions containing DNAs of known base composition, specifically evidenced by 2,7-di-t-butyl proflavine

@article{Distche1974ChromosomeRC,
  title={Chromosome regions containing DNAs of known base composition, specifically evidenced by 2,7-di-t-butyl proflavine},
  author={Christine Dist{\`e}che and J. Bontemps},
  journal={Chromosoma},
  year={1974},
  volume={47},
  pages={263-281}
}
After staining by a new proflavine derivative (2,7-di-t-butyl proflavine, DBP), which specifically binds to the A-T base pairs of DNA by an external process, the constrictions of the human chromosomes 1, 16 and to a lesser extent 9 and the centromeric regions of the chromosomes (except the Y) of Mus musculus are brightly fluorescent. These chromosome regions are known to contain repetitive DNAs rich in A-T. On the contrary, the centromeric regions of the autosomes of Bos taurus, which contain a… CONTINUE READING

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