Chromosome pairing and germ cell loss in male and female mice carrying a reciprocal translocation.

Abstract

Female carriers of the T(5;12)31H reciprocal translocation had an average reduction of 73% in oocyte numbers compared with normal litter mates, which was of a magnitude similar to the reduction in sperm counts of male carriers. Analysis of synaptonemal complexes showed that the translocated chromosomes appeared as quadrivalents, or trivalents and univalents… (More)

10 Figures and Tables

Topics

  • Presentations referencing similar topics