Chromosome ends: different sequences may provide conserved functions.

@article{Louis2005ChromosomeED,
  title={Chromosome ends: different sequences may provide conserved functions.},
  author={Edward J Louis and Alexander V. Vershinin},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={2005},
  volume={27 7},
  pages={685-97}
}
The structures of specific chromosome regions, centromeres and telomeres, present a number of puzzles. As functions performed by these regions are ubiquitous and essential, their DNA, proteins and chromatin structure are expected to be conserved. Recent studies of centromeric DNA from human, Drosophila and plant species have demonstrated that a hidden universal centromere-specific sequence is highly unlikely. The DNA of telomeres is more conserved consisting of a tandemly repeated 6-8 bp… CONTINUE READING

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