Chromosome analysis of brain tumors in childhood.

@article{Fujii1994ChromosomeAO,
  title={Chromosome analysis of brain tumors in childhood.},
  author={Yoshitaka Fujii and Takuya Hongo and M D Yasuhide Hayashi},
  journal={Genes, chromosomes & cancer},
  year={1994},
  volume={11 4},
  pages={
          205-15
        }
}
We performed a chromosome analysis of 26 pediatric brain tumors, including 20 primitive neuroectodermal tumors (PNETs). 5 astrocytomas, and 1 immature teratoma. Specimens were treated with collagenase, placed in overnight or short-term cultures, and harvested for chromosome analysis. Numerical and/or structural abnormalities were noted in 14 of the 20 PNETs and 4 of the 5 astrocytomas. In 13 PNETs, so-called medulloblastoma in the cerebellum, an i(17q) was the most frequent structural… CONTINUE READING
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