Chromosome aberrations induced by pyrolysates of carbohydrates in Chinese hamster V79 cells.

@article{Nishi1989ChromosomeAI,
  title={Chromosome aberrations induced by pyrolysates of carbohydrates in Chinese hamster V79 cells.},
  author={Yoshisuke Nishi and Yozo Miyakawa and Kazunori Kato},
  journal={Mutation research},
  year={1989},
  volume={227 2},
  pages={117-23}
}
The clastogenic activity of some pyrolysates of carbohydrates was examined in cultured Chinese hamster V79 cells. These pyrolysates include levoglucosan (LG-I), levoglucosenone (LG-II), furfural (FF), 5-(hydroxymethyl)-2-furfural (HMF), glyoxal (GL), methylglyoxal (MGL), 3-deoxy-D-glucosone (DG) and thiazolidine (TZ). LG-I did not induce a significant number of chromosome aberrations at doses up to 8000 micrograms/ml. In contrast, the related compound LG-II induced aberrations and reduced… CONTINUE READING

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