Chromosome Segregation: Keeping Kinetochores in the Loop


The Ndc80 complex is a key component of the kinetochore-microtubule interface. Two studies now demonstrate that a conserved loop region within the extended coiled-coil of Ndc80 plays an unexpected role in recruiting proteins to the kinetochore.

DOI: 10.1016/j.cub.2010.12.030

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@article{Schmidt2011ChromosomeSK, title={Chromosome Segregation: Keeping Kinetochores in the Loop}, author={J. Christian Schmidt and Iain M Cheeseman}, journal={Current Biology}, year={2011}, volume={21}, pages={R110-R112} }