Chromosome Segregation Is Biased by Kinetochore Size

  title={Chromosome Segregation Is Biased by Kinetochore Size},
  author={Danica Drpic and Ana Carolina da Veiga Rodarte de Almeida and Paulo de Castro Aguiar and Fioranna Renda and Joana Damas and Harris A. Lewin and Denis M. Larkin and Alexey Khodjakov and Helder Maiato},
  booktitle={Current Biology},
Chromosome missegregation during mitosis or meiosis is a hallmark of cancer and the main cause of prenatal death in humans. The gain or loss of specific chromosomes is thought to be random, with cell viability being essentially determined by selection. Several established pathways including centrosome amplification, sister-chromatid cohesion defects, or a… CONTINUE READING