Chromosome Conformation Capture Carbon Copy (5C) in Budding Yeast.

Abstract

Chromosome conformation capture carbon copy (5C) is a high-throughput method for detecting ligation products of interest in a chromosome conformation capture (3C) library. 5C uses ligation-mediated amplification (LMA) to generate carbon copies of 3C ligation product junctions using single-stranded oligonucleotide probes. This procedure produces a 5C library… (More)
DOI: 10.1101/pdb.prot085191

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