Chromosome 8p deletions and 8q gains are associated with tumor progression and poor prognosis in prostate cancer.


PURPOSE Deletions of 8p and gains of 8q belong to the most frequent cytogenetic alterations in prostate cancer. The target genes of these alterations and their biological significance are unknown. EXPERIMENTAL DESIGN To determine the relationship between chromosome 8 changes, and prostate cancer phenotype and prognosis, a set of 1.954 fully annotated… (More)
DOI: 10.1158/1078-0432.CCR-09-1423


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