Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer

@article{TabarsSeisdedos2009Chromosome8A,
  title={Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer},
  author={Rafael Tabar{\'e}s-Seisdedos and John L. R. Rubenstein},
  journal={Molecular Psychiatry},
  year={2009},
  volume={14},
  pages={563-589}
}
Defects in genetic and developmental processes are thought to contribute susceptibility to autism and schizophrenia. Presumably, owing to etiological complexity identifying susceptibility genes and abnormalities in the development has been difficult. However, the importance of genes within chromosomal 8p region for neuropsychiatric disorders and cancer is well established. There are 484 annotated genes located on 8p; many are most likely oncogenes and tumor-suppressor genes. Molecular genetics… Expand
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