Chromosome 1p and 19q deletions in glioblastoma multiforme.

  title={Chromosome 1p and 19q deletions in glioblastoma multiforme.},
  author={David K Kaneshiro and Taisei Kobayashi and Samuel Tay Chao and John Suh and Richard A. Prayson},
  journal={Applied immunohistochemistry & molecular morphology : AIMM},
  volume={17 6},
CONTEXT Deletions on chromosomes 1p and 19q have been shown to correlate with prognosis and chemosensitivity in anaplastic oligodendrogliomas. In glioblastoma multiforme (GBM), the impact on prognosis of these alterations in GBM is unclear. OBJECTIVE The purpose of this study was to identify patients with GBM who had evidence of 1p or 19q deletions by fluorescence in situ hybridization, and correlate these results with clinical findings and survival. DESIGN Three hundred thirty-seven GBM… CONTINUE READING