Chromosome 17 and the inducible nitric oxide synthase gene in human essential hypertension

@article{Rutherford2001Chromosome1A,
  title={Chromosome 17 and the inducible nitric oxide synthase gene in human essential hypertension},
  author={Stephen Graham Rutherford and Matthew P Johnson and Robert P. Curtain and Lyn R Griffiths},
  journal={Human Genetics},
  year={2001},
  volume={109},
  pages={408-415}
}
Abstract. Essential hypertension is a common multifactorial trait that results in a significantly increased risk for heart attack and stroke. The condition has a genetic basis, although at present the number of genes is unknown. In order to identify such genes, we are utilising a linkage scanning approach using microsatellite markers and affected sibships. Here we provide evidence for the location of at least one hypertension susceptibility locus on chromosome 17. Analysis of 177 affected… CONTINUE READING
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