Chromosomally encoded blaCMY-2 located on a novel SXT/R391-related integrating conjugative element in a Proteus mirabilis clinical isolate.

@article{Harada2010ChromosomallyEB,
  title={Chromosomally encoded blaCMY-2 located on a novel SXT/R391-related integrating conjugative element in a Proteus mirabilis clinical isolate.},
  author={Sohei Harada and Yoshikazu Ishii and Tomoo Saga and Kazuhiro Tateda and Keizo Yamaguchi},
  journal={Antimicrobial agents and chemotherapy},
  year={2010},
  volume={54 9},
  pages={3545-50}
}
Integrating conjugative elements (ICEs) are mobile genetic elements that can transfer from the chromosome of a host to the chromosome of a new host through the process of excision, conjugation, and integration. Although SXT/R391-related ICEs, originally demonstrated in Vibrio cholerae O139 isolates, have become prevalent among V. cholerae isolates in Asia, the prevalence of the ICEs among gram-negative bacteria other than Vibrio spp. remains unknown. In addition, SXT/R391-related ICEs carrying… CONTINUE READING