Chromosomal rearrangements during human epidermal keratinocyte differentiation.

Abstract

Undifferentiated human epidermal keratinocytes are self-renewing stem cells that can be induced to undergo a program of differentiation by varying the calcium chloride concentration in the culture media. We utilize this model of cell differentiation and a 3D chromosome painting technique to document significant changes in the radial arrangement, morphology… (More)
DOI: 10.1002/jcp.21855

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