Chromosomal passengers: conducting cell division

@article{Ruchaud2007ChromosomalPC,
  title={Chromosomal passengers: conducting cell division},
  author={Sandrine Ruchaud and Mar Carmena and William C Earnshaw},
  journal={Nature Reviews Molecular Cell Biology},
  year={2007},
  volume={8},
  pages={798-812}
}
Mitosis and meiosis are remarkable processes during which cells undergo profound changes in their structure and physiology. These events are orchestrated with a precision that is worthy of a classical symphony, with different activities being switched on and off at precise times and locations throughout the cell. One essential 'conductor' of this symphony is the chromosomal passenger complex (CPC), which comprises Aurora-B protein kinase, the inner centromere protein INCENP, survivin and… CONTINUE READING
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