Chromosomal microarray analysis and prenatal diagnosis.

  title={Chromosomal microarray analysis and prenatal diagnosis.},
  author={Jamie Oi-Ting Lo and Brian L Shaffer and Cori D. Feist and Aaron B Caughey},
  journal={Obstetrical & gynecological survey},
  volume={69 10},
Chromosomal microarray analysis (CMA) assesses chromosomal copy number alterations and affords higher resolution when compared with standard karyotype. This review provides the obstetric provider with an update on the technology, use, and controversies concerning CMA utilization in prenatal diagnosis. Chromosomal microarray analysis offers increased resolution for copy number abnormalities compared with traditional karyotype. There is high-quality evidence for the added detection of clinically… CONTINUE READING
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