Chromosomal localization of the human and mouse hyaluronan synthase genes.

@article{Spicer1997ChromosomalLO,
  title={Chromosomal localization of the human and mouse hyaluronan synthase genes.},
  author={Andrew P. Spicer and Michael F. Seldin and Anne Sofie Westh Olsen and Nkecha Brown and Dan E. Wells and Norman A. Doggett and Naoki Itano and Koji Kimata and Johji Inazawa and John Alan McDonald},
  journal={Genomics},
  year={1997},
  volume={41 3},
  pages={
          493-7
        }
}
We have recently identified a new vertebrate gene family encoding putative hyaluronan (HA) synthases. Three highly conserved related genes have been identified, designated HAS1, HAS2, and HAS3 in humans and Has1, Has2, and Has3 in the mouse. All three genes encode predicted plasma membrane proteins with multiple transmembrane domains and approximately 25% amino acid sequence identity to the Streptococcus pyogenes HA synthase, HasA. Furthermore, expression of any one HAS gene in transfected… CONTINUE READING
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