Chromosomal localization of the human NF-E2 family of bZIP transcription factors by fluorescence in situ hybridization

@article{Chan2004ChromosomalLO,
  title={Chromosomal localization of the human NF-E2 family of bZIP transcription factors by fluorescence in situ hybridization},
  author={J. Y. Chan and Mei-Chi Cheung and P. Moi and K. Chan and Y. Kan},
  journal={Human Genetics},
  year={2004},
  volume={95},
  pages={265-269}
}
  • J. Y. Chan, Mei-Chi Cheung, +2 authors Y. Kan
  • Published 2004
  • Biology, Medicine
  • Human Genetics
  • A family of human genes encoding basic-leucine zipper (bZIP) transcription factors, p45-NF-E2, Nrf1 and Nrf2, have been isolated independently. Whereas the encoded proteins of the three genes share highly conserved regions distinct from other bZIP families such as Jun or Fos, remaining regions diverged considerably from each other. Chromosomal localization by fluorescence insitu hybridization demonstrates that these genes are nonsyntenic. p45-NF-E2 mapped to chromosome 12q13.1–13.3, whereas… CONTINUE READING
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