Chromosomal localization of GPR48, a novel glycoprotein hormone receptor like GPCR, in human and mouse with radiation hybrid and interspecific backcross mapping.

@article{Loh2000ChromosomalLO,
  title={Chromosomal localization of GPR48, a novel glycoprotein hormone receptor like GPCR, in human and mouse with radiation hybrid and interspecific backcross mapping.},
  author={Eddie Loh and Shorna Broussard and Qing-Rong Liu and Neal G. Copeland and Debra J. Gilbert and Nancy A. Jenkins and Lee F. Kolakowski},
  journal={Cytogenetics and cell genetics},
  year={2000},
  volume={89 1-2},
  pages={
          2-5
        }
}
We report the chromosomal localization in both mouse and human of a novel G-protein-coupled receptor, GPR48, which resembles glycoprotein hormone receptors, that may be implicated in Wilms tumor deletion syndromes such as WAGR. This receptor forms a novel sub-family of glycoprotein hormone-like GPCRs. We have mapped this receptor to human chromosome 11p14-->p13 by several approaches, including radiation hybrid and interspecific backcross mapping, and show that GPR48 is close to BDNF. This data… CONTINUE READING
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