Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene family.

@article{Hemmerich2001ChromosomalLA,
  title={Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene family.},
  author={Stefan Hemmerich and Jin Kyu Lee and Sunil B. Bhakta and Annette Bistrup and N R Ruddle and S D Rosen},
  journal={Glycobiology},
  year={2001},
  volume={11 1},
  pages={
          75-87
        }
}
The galactose/N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferases (GSTs) are a family of Golgi-resident enzymes that transfer sulfate from 3'phosphoadenosine 5'phospho-sulfate to the 6-hydroxyl group of galactose, N-acetylgalactosamine, or N-acetylglucosamine in nascent glycoproteins. These sulfation modifications are functionally important in settings as diverse as cartilage structure and lymphocyte homing. To date six members of this gene family have been described in human and in… CONTINUE READING
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