Chromosomal instability in peripheral blood lymphocytes and risk of prostate cancer.

@article{ElZein2005ChromosomalII,
  title={Chromosomal instability in peripheral blood lymphocytes and risk of prostate cancer.},
  author={Randa El-Zein and Yun Gu and M Dolores Saco Sierra and Margaret R. Spitz and Sara S. Strom},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2005},
  volume={14 3},
  pages={748-52}
}
Prostate cancer is an extremely complex disease, and it is likely that chromosomal instability is involved in the genetic mechanism of tumorigenesis. Several chromosomes have been labeled as "players" in the development of prostate cancer, among them chromosome 1 and X chromosome have been reported to harbor prostate cancer susceptibility loci. However, there is little information regarding the background levels of chromosome instability in these patients. In this pilot study, we examined… CONTINUE READING
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