Chromosomal insertion sites for phages and plasmids.

  title={Chromosomal insertion sites for phages and plasmids.},
  author={Allan M. Campbell},
  journal={Journal of bacteriology},
  volume={174 23},
Bacteriophages insert their DNA into host chromosomes either through transposition (as in phage Mu) or through site-specific recombination (as in phage X). Whereas Mu can insert almost anywhere along the chromosome, X has a single highly preferred chromosomal site. Certain plasmids also insert into chromosomes by site-specific recombination. The site-specific recombinases used generally belong to the integrase family, whose members show some sequence homology and conservation of reaction… CONTINUE READING