Chromosomal changes in betel-associated oral squamous cell carcinomas and their relationship to clinical parameters.

@article{Lin2002ChromosomalCI,
  title={Chromosomal changes in betel-associated oral squamous cell carcinomas and their relationship to clinical parameters.},
  author={Shu Chun Lin and Yann Jang Chen and Shou Yen Kao and Ming Ta Hsu and Chi Hong Lin and Shun Chun Yang and Tsung Yun Liu and Kuo wei Chang},
  journal={Oral oncology},
  year={2002},
  volume={38 3},
  pages={266-73}
}
To investigate the chromosomal imbalances that occur in oral carcinoma associated primarily with betel use and their clinical implications, we performed chromosomal analysis using comparative genomic hybridization on 47 patients with this disease. The most common gains of chromosome arms were 8q, 9q and 11q, and the most frequent losses were of chromosomal arms 3p and 4q. The clinical parameters significantly associated with the numbers of chromosomal imbalances per tumor were the age of the… CONTINUE READING