Chromosomal abnormalities: a potential quality issue for cloned cattle embryos.

@article{SlimaneBureau2002ChromosomalAA,
  title={Chromosomal abnormalities: a potential quality issue for cloned cattle embryos.},
  author={Wafa C Slimane-Bureau and William Allan King},
  journal={Cloning and stem cells},
  year={2002},
  volume={4 4},
  pages={
          319-29
        }
}
Nuclear transfer in cattle is associated with high levels of embryonic mortality and often with congenital malformation. Chromosomal abnormalities are a well-known cause of pregnancy failure and congenital malformation in humans, but their relative contribution to pregnancy failure and congenital malformation in cloned embryos and calves is largely unknown. This paper reviews existing literature on the chromosomal constitution of bovine embryos produced by fertilization in vivo and in vitro… CONTINUE READING
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