Chromosomal aberrations involving telomeres and interstitial telomeric sequences.


Telomeres are specialised nucleoproteic complexes localised at the physical ends of linear eukaryotic chromosomes that maintain their stability and integrity. In vertebrate chromosomes, the DNA component of telomeres is constituted by (TTAGGG)n repeats, which can be localised at the terminal regions of chromosomes (true telomeres) or at intrachromosomal… (More)
DOI: 10.1093/mutage/ger052


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