Chromosomal Duplication Accompanies Allelic Loss in Non-Small Cell Lung Carcinoma 1

@inproceedings{VarellaGarcia2006ChromosomalDA,
  title={Chromosomal Duplication Accompanies Allelic Loss in Non-Small Cell Lung Carcinoma 1},
  author={Marileila Varella-Garcia and Robert M. Gemmili and Silvia HB Rabenhorst and Alice Lotto and Harry A. Drabkin and Philip A. Archer and Wilbur A. Franklin},
  year={2006}
}
Hemizygous deletion in the short (p) arm of chromosome 3 is a common finding in non-small cell lung carcinoma (NSCLC) and is postulated to be a crucial early change in lung tumorigenesis. Yet one of the most frequent nuclear abnormalities in both NSCLC and premalignant bronchial epi thelium is increase in chromosomal copy number. Deletion and duplica tion… CONTINUE READING