Chromogranin peptides in Alzheimer's disease.

  title={Chromogranin peptides in Alzheimer's disease.},
  author={Theresa Lechner and Christine Adlassnig and Christian Humpel and Walter A. Kaufmann and Hans Maier and Karin Reinstadler-Kramer and Josef K Hinterhoelzl and Sushil K Mahata and Kurt A. Jellinger and Josef J. M. Marksteiner},
  journal={Experimental gerontology},
  volume={39 1},
Synaptic disturbances may play a key role in the pathophysiology of Alzheimer's disease. To characterize differential synaptic alterations in the brains of Alzheimer patients, chromogranin A, chromogranin B and secretoneurin were applied as soluble constituents for large dense core vesicles, synaptophysin as a vesicle membrane marker and calbindin as a… CONTINUE READING