Chromogranin A in the mammalian Merkel cell: cellular and subcellular distribution.

  title={Chromogranin A in the mammalian Merkel cell: cellular and subcellular distribution.},
  author={Wolfgang Hartschuh and Eberhard Weihe and Ursula Egner},
  journal={The Journal of investigative dermatology},
  volume={93 5},
Chromogranin-A (CGA), which accounts for more than half the soluble matrix protein in secretory granules of various neuroendocrine cells, has a wide spectrum of potential biological roles and is considered an important marker of the diffuse neuroendocrine system (DNES). Light and electron microscopic immunohistochemistry of mammalian skin revealed that Merkel cells are exclusively CGA-immunoreactive (ir) and that the immunoreaction is localized in the secretory granules. This finding supports… CONTINUE READING

From This Paper

Topics from this paper.
14 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 14 extracted citations

Similar Papers

Loading similar papers…