Chromogranin A in diagnosing and monitoring patients with gastroenteropancreatic neuroendocrine neoplasms: a large series from a single institution.

@article{Massironi2014ChromograninAI,
  title={Chromogranin A in diagnosing and monitoring patients with gastroenteropancreatic neuroendocrine neoplasms: a large series from a single institution.},
  author={Sara Massironi and Roberta Elisa Rossi and Giovanni Casazza and Dario Conte and Clorinda Ciafardini and Marianna Galeazzi and Maddalena Peracchi},
  journal={Neuroendocrinology},
  year={2014},
  volume={100 2-3},
  pages={240-9}
}
BACKGROUND/AIMS Plasma chromogranin A (CgA) is the most widely used biochemical biomarker in the diagnostic workup and follow-up of gastroenteropancreatic neuroendo- crine neoplasms (GEP-NENs). Herein, we assessed the clinical utility of CgA in diagnosing and monitoring a large series of GEP-NENs. PATIENTS AND METHODS A total of 181 GEP-NEN patients (87 males, 94 females) with pancreatic (n = 81) and gastrointestinal neoplasms (n = 100) were included; 99 patients had grade (G)1 NENs (Ki-67 ≤2… CONTINUE READING
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