Chromogranin A: localization and stoichiometry in large dense core catecholamine storage vesicles from sympathetic nerve.

Abstract

Chromogranin A is present in both adrenal medullary chromaffin granules and sympathetic nerve large dense core catecholamine storage vesicles (LDVs), yet selective stimulation of sympathetic axons provokes only minor changes in chromogranin A in the circulation. We therefore examined the stoichiometry of chromogranin A storage in purified LDVs as compared… (More)

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