Chromogenic peptide substrate assays in patients with multiple trauma.

  title={Chromogenic peptide substrate assays in patients with multiple trauma.},
  author={Peter B Kierulf and Ansgar Oddne Aasen and Steinar Aune and Hans C Godal and Tom Erik Ruud and Jarle I. Vaage},
  journal={Acta chirurgica Scandinavica. Supplementum},
Daily monitoring of the plasma proteolytic enzyme systems i.e. the coagulation, the fibrinolytic and the kallikrein-kinin system in multitraumatized patients with chromogenic substrate assays disclosed significant differences in the levels of Prekallikrein, Hageman Factor, Antithrombin-III, Prothrombin in survivors (N = 9) and fatal cases (N = 6) during the first week after admission. Since chromogenic peptide substrate assays are simple, cheap and easily automated, close monitoring of critical… CONTINUE READING

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