Chromogenic In Situ Hybridization: A Novel Approach to a Practical and Sensitive Method for the Detection of HER2 Oncogene in Archival Human Breast Carcinoma

@article{Dandachi2002ChromogenicIS,
  title={Chromogenic In Situ Hybridization: A Novel Approach to a Practical and Sensitive Method for the Detection of HER2 Oncogene in Archival Human Breast Carcinoma},
  author={Nadia Dandachi and Otto Dietze and Cornelia Hauser-kronberger},
  journal={Laboratory Investigation},
  year={2002},
  volume={82},
  pages={1007-1014}
}
The high incidence of HER2 overexpression on the cell surface of breast cancer cells and the recognized prognostic and potentially predictive value of HER2 render this cell surface receptor a novel and important therapeutic target. Although immunohistochemistry (IHC; HercepTest) and fluorescence in situ hybridization (FISH; PathVysion and INFORM)—both approved by the Food and Drug Administration—have emerged as the most viable assays for evaluation of HER2 status in routine clinical practice… CONTINUE READING
48 Citations
31 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 48 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 31 references

Assessment of the need and appropriate method for testing for the human epidermal growth factor receptor-2 (HER2)

  • MJ van de Vijver
  • Eur J Cancer
  • 2001
1 Excerpt

Similar Papers

Loading similar papers…