Chromium supplementation in overweight and obesity: a systematic review and meta‐analysis of randomized clinical trials

@article{Onakpoya2013ChromiumSI,
  title={Chromium supplementation in overweight and obesity: a systematic review and meta‐analysis of randomized clinical trials},
  author={Igho J. Onakpoya and Paul Posadzki and Edzard Ernst},
  journal={Obesity Reviews},
  year={2013},
  volume={14}
}
The increased prevalence of obesity has made the use of dietary supplements as weight reducing agents highly popular, but their efficacy has not been proven. One such supplement is chromium. The purpose of this review was to evaluate the evidence for or against the efficacy of chromium supplementation in overweight and obese individuals. Electronic searches were conducted in Medline, Embase, Amed and The Cochrane Library. The bibliographies of located articles were also searched. No age, gender… 
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References

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TLDR
A relatively small effect of chromium picolinate compared with placebo for reducing body weight is suggested, but the clinical relevance of the effect is debatable and the lack of robustness means that the result has to be interpreted with caution.
A pilot study of chromium picolinate for weight loss.
BACKGROUND Chromium is an essential trace element and nutritional supplement that has garnered interest for use as a weight loss aid. OBJECTIVE This trial assesses the effects of chromium
Beneficial Effect of Chromium Supplementation on Serum Triglyceride Levels in NIDDM
TLDR
This is the first report of a significant reduction in serum TGs in a group of NIDDM patients treated with chromium, making it an attractive lipid-lowering agent for this population.
A Double-Blind, Placebo-Controlled, Exploratory Trial of Chromium Picolinate in Atypical Depression: Effect on Carbohydrate Craving
TLDR
The results of this study suggest that the main effect of chromium was on carbohydrate craving and appetite regulation in depressed patients and that 600 μg of elemental chromium may be beneficial for patients with atypical depression who also have severe carbohydrate craving.
Effects of chromium picolinate on body composition.
TLDR
It was concluded that chromium picolinate was ineffective in enhancing body fat reduction in this group and could not be recommended as an adjuvant to Navy weight-loss programs in general.
In patients with HIV-infection, chromium supplementation improves insulin resistance and other metabolic abnormalities: a randomized, double-blind, placebo controlled trial.
TLDR
It is suggested that chromium supplements alleviate some of the antiretroviral-associated metabolic abnormalities in HIV+ patients, and body weight and medication profile remained stable throughout the study for both groups.
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TLDR
The objective of this overview was to summarize and critically evaluate all available systematic reviews of food supplements for body weight reduction.
The Potential Value and Toxicity of Chromium Picolinate as a Nutritional Supplement, Weight Loss Agent and Muscle Development Agent
TLDR
Over a decade of human studies with Cr(pic)3 indicate that the supplement has not demonstrated effects on the body composition of healthy individuals, even when taken in combination with an exercise training programme.
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