Chromium-induced biochemical, genotoxic and histopathologic effects in liver and kidney of goldfish, carassius auratus.

@article{Velma2010ChromiuminducedBG,
  title={Chromium-induced biochemical, genotoxic and histopathologic effects in liver and kidney of goldfish, carassius auratus.},
  author={V. Velma and P. Tchounwou},
  journal={Mutation research},
  year={2010},
  volume={698 1-2},
  pages={
          43-51
        }
}
  • V. Velma, P. Tchounwou
  • Published 2010
  • Medicine, Biology
  • Mutation research
  • Fish constitute an excellent model to understand the mechanistic aspects of metal toxicity vis-à-vis oxidative stress in aquatic ecosystems. Hexavalent chromium (Cr (VI)), due to its redox potential can induce oxidative stress (OS) in fish and impair their health. In the present investigation, we hypothesize that OS plays a key role in chromium induced toxicity in goldfish; leading to the production of reactive oxygen species (ROS) such as O(.)(2), H(2)O(2), OH(.), and subsequent modulation of… CONTINUE READING

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