Chromium (VI) Can Activate and Impair Antioxidant Defense System

@article{Asatiani2010ChromiumC,
  title={Chromium (VI) Can Activate and Impair Antioxidant Defense System},
  author={Nino Asatiani and Tamar Kartvelishvili and Marina K. Abuladze and Lali Asanishvili and Nelly A. Sapojnikova},
  journal={Biological Trace Element Research},
  year={2010},
  volume={142},
  pages={388-397}
}
The changes in glutathione-dependent cycle enzymes and catalase activities under Cr(VI)-induced oxidative stress were investigated in two distinct cell lines: L-41−human epithelial-like cells and HLF−fetal human diploid lung fibroblasts, which differ in tissue origin, proliferation, and antioxidant enzymes activities. The chromium concentrations from 1 to 5 μM cause nontoxic effects and activate antioxidant enzymes to overcome oxidative stress. In spite of some differences in the endogenous… CONTINUE READING

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