Chromatography of benzodiazepines.

  title={Chromatography of benzodiazepines.},
  author={Antoine Sioufi and Jean-Christophe Dubois},
  journal={Journal of chromatography},
An overview of methods for the determination of benzodiazepines in biological media, based on the application of chromatographic techniques, is presented. A general discussion of the techniques in terms of stability, selectivity, validation, standardization, detection and sensitivity is given. No single technique can be claimed as the method of choice for benzodiazepines. Gas chromatography with electron-capture detection has some strong claims and shows generally good sensitivity and… CONTINUE READING