Chromatography and Atomic Absorption Spectrometry for the Assessment of Heavy Metal Distribution among Amino Acids Used in Parenteral Nutrition Formulations—Studies with Cadmium and Lead

@article{Nascimento2010ChromatographyAA,
  title={Chromatography and Atomic Absorption Spectrometry for the Assessment of Heavy Metal Distribution among Amino Acids Used in Parenteral Nutrition Formulations—Studies with Cadmium and Lead},
  author={Paulo C{\'i}cero do Nascimento and Marieli S. da Marques and Denise Bohrer and Leandro Machado de Carvalho and Claudia W. Carvalho},
  journal={Biological Trace Element Research},
  year={2010},
  volume={141},
  pages={76-85}
}
The distribution of Cd (II) and Pb (II) among amino acids in parenteral nutrition formulations was investigated by coupling ion-chromatography (HPLC/IC) and electrothermal atomic absorption spectrometry. The methodology was based on ion-exchange separation and fluorimetric amino acid detection after post-column derivatization. Cd (II) and Pb (II) were… CONTINUE READING